Opportunity Information: Apply for PAR 15 342
The NCI Outstanding Investigator Award (R35), announced by the National Institutes of Health under FOA number PAR-15-342, is a discretionary grant opportunity designed to support high-level cancer research in any scientific area relevant to cancer. The core idea of this award is to provide substantial, stable funding to investigators so they can pursue ambitious, long-range research programs rather than being limited to short, narrowly defined projects. Because it is framed broadly as "any area of cancer research," the opportunity can cover a wide range of topics, including basic, translational, clinical, prevention, population, behavioral, and other cancer-related research, as long as the work aligns with the National Cancer Institute mission and priorities.
In terms of funding structure, this opportunity is offered as a grant, with an indicated award ceiling of $600,000. While the source data does not specify the exact number of expected awards, it does indicate that the program is intended to make one or more awards depending on application volume, program priorities, and available funds. The Catalog of Federal Domestic Assistance (CFDA) numbers associated with this opportunity are 93.393 through 93.399, reflecting that it sits within NIH and NCI research support mechanisms that span multiple cancer-related assistance listings. The original closing date listed for this particular announcement cycle was January 7, 2016, and the record shows a creation date of September 3, 2015, which signals that applicants needed to plan around a traditional NIH application timeline and policies in effect for that period.
Eligibility is broad across the U.S. research ecosystem and includes many common applicant types: state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; nonprofits (both those with 501(c)(3) status and those without, as long as they are not institutions of higher education in the nonprofit category listed); for-profit organizations other than small businesses; and small businesses. It also includes Native American tribal governments that are federally recognized, as well as Native American tribal organizations that are not federally recognized tribal governments. Public housing authorities and Indian housing authorities are also listed as eligible.
The FOA also explicitly highlights additional categories of eligible applicants, emphasizing inclusion of a wide range of institution types and community-connected organizations. These include Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); and Tribally Controlled Colleges and Universities (TCCUs). It also notes faith-based or community-based organizations, regional organizations, eligible federal agencies, U.S. territories or possessions, and Indian/Native American tribal governments other than federally recognized entities as eligible in the contexts described.
At the same time, the announcement draws clear boundaries around foreign involvement. Non-domestic (non-U.S.) entities, meaning foreign institutions, are not eligible to apply as the applicant organization. Similarly, non-domestic components of U.S. organizations are not eligible to apply. However, the FOA allows foreign components as defined in the NIH Grants Policy Statement, meaning that while the main applicant must be a U.S.-based eligible organization, certain parts of the research activities may involve foreign collaborations or performance sites if they meet NIH definitions and requirements and if the application justifies the need for that foreign component.
Overall, this R35 opportunity can be understood as a major NCI mechanism meant to back outstanding cancer researchers with sizable support and flexibility, while still operating within standard NIH grants rules on eligibility, institutional applicant types, and the permitted scope of any international collaboration.Apply for PAR 15 342
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "NCI Outstanding Investigator Award (R35)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393, 93.394, 93.395, 93.396, 93.397, 93.398, 93.399.
- This funding opportunity was created on 2015-09-03.
- Applicants must submit their applications by 2016-01-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $600,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs): NCI Outstanding Investigator Award (R35) - PAR-15-342
What is the NCI Outstanding Investigator Award (R35)?
The NCI Outstanding Investigator Award (R35) is a discretionary grant opportunity from the National Institutes of Health (NIH), through the National Cancer Institute (NCI). It is designed to provide substantial, stable support for high-level cancer research so investigators can pursue ambitious, long-range research programs rather than being restricted to short, narrowly defined projects.
Which agency is offering this funding opportunity?
This opportunity is offered by the National Institutes of Health (NIH) under the National Cancer Institute (NCI).
What is the FOA number for this opportunity?
The Funding Opportunity Announcement (FOA) number is PAR-15-342.
What kind of research does this award support?
The award supports cancer research in any scientific area relevant to cancer, as long as the proposed work aligns with the mission and priorities of the National Cancer Institute (NCI). The scope is intentionally broad to enable long-range, high-impact research programs.
What research areas are included under "any area of cancer research"?
Based on the information provided, the opportunity can cover a wide range of cancer-related research areas, including basic, translational, clinical, prevention, population, and behavioral research, as well as other cancer-relevant scientific topics consistent with NCI priorities.
What type of funding mechanism is this?
This opportunity is offered as a grant.
What is the maximum (ceiling) award amount?
The indicated award ceiling is $600,000.
How many awards does the program expect to make?
The source information does not specify an exact number of awards. It indicates that the program intends to make one or more awards depending on application volume, program priorities, and available funds.
What are the CFDA numbers associated with this opportunity?
The Catalog of Federal Domestic Assistance (CFDA) numbers listed for this opportunity are 93.393 through 93.399.
When was this opportunity created?
The record shows a creation date of September 3, 2015.
What was the closing date for this announcement cycle?
The original closing date listed for this particular announcement cycle was January 7, 2016.
Who can apply (general eligibility)?
Eligibility is broad and includes many types of U.S. organizations across the research ecosystem, including various levels of government, educational institutions, nonprofits, and businesses, as well as tribal entities and housing authorities, as specifically listed in the opportunity information.
Are state, local, or special district governments eligible to apply?
Yes. The listed eligible applicants include state governments, county governments, city or township governments, and special district governments.
Are public and private colleges and universities eligible to apply?
Yes. Eligible applicants include public and state-controlled institutions of higher education as well as private institutions of higher education.
Are independent school districts eligible to apply?
Yes. Independent school districts are listed as eligible applicants.
Are nonprofit organizations eligible to apply?
Yes. The eligibility list includes nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status, with the condition noted in the source information that these nonprofit categories are those that are not institutions of higher education in the nonprofit category listed.
Are for-profit organizations eligible to apply?
Yes. The eligibility list includes for-profit organizations other than small businesses, and it separately includes small businesses as eligible applicants.
Are small businesses eligible to apply?
Yes. Small businesses are explicitly listed as eligible.
Are Native American tribal governments eligible to apply?
Yes. The eligibility list includes federally recognized Native American tribal governments. It also includes other Indian/Native American tribal governments in the contexts described in the opportunity information, as well as Native American tribal organizations that are not federally recognized tribal governments.
Are Native American tribal organizations (not federally recognized) eligible?
Yes. Native American tribal organizations that are not federally recognized tribal governments are listed as eligible applicants.
Are public housing authorities eligible to apply?
Yes. Public housing authorities and Indian housing authorities are listed as eligible applicants.
Are U.S. territories or possessions eligible to apply?
Yes. U.S. territories or possessions are included among the eligible applicant categories as described in the opportunity information.
Are faith-based or community-based organizations eligible to apply?
Yes. The FOA notes faith-based or community-based organizations as eligible.
Are minority-serving institutions specifically recognized as eligible?
Yes. The opportunity explicitly highlights a number of institution types, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and other community-connected organizations described in the eligibility section.
Are Alaska Native and Native Hawaiian Serving Institutions eligible?
Yes. Alaska Native and Native Hawaiian Serving Institutions are explicitly listed as eligible.
Are AANAPISIs eligible?
Yes. Asian American Native American Pacific Islander Serving Institutions (AANAPISIs) are explicitly listed as eligible.
Are Hispanic-serving Institutions eligible?
Yes. Hispanic-serving Institutions are explicitly listed as eligible.
Are HBCUs eligible?
Yes. Historically Black Colleges and Universities (HBCUs) are explicitly listed as eligible.
Are TCCUs eligible?
Yes. Tribally Controlled Colleges and Universities (TCCUs) are explicitly listed as eligible.
Can foreign (non-U.S.) organizations apply as the main applicant?
No. Non-domestic (non-U.S.) entities are not eligible to apply as the applicant organization.
Can a non-domestic component of a U.S. organization apply?
No. Non-domestic components of U.S. organizations are not eligible to apply as the applicant.
Is any foreign involvement allowed at all?
Yes. While the main applicant must be a U.S.-based eligible organization, the FOA allows foreign components as defined in the NIH Grants Policy Statement. In practical terms, this means certain research activities may involve foreign collaborations or performance sites if they meet NIH definitions and requirements and the application justifies the need for that foreign component.
What is the main purpose of providing "stable" funding under this award?
The core purpose is to give outstanding investigators flexibility and stability to pursue ambitious, long-range cancer research programs, rather than forcing the work into short, narrowly defined projects.
Does this opportunity restrict research to a single cancer research domain (for example, only basic or only clinical)?
No. The opportunity is framed broadly as supporting any scientific area relevant to cancer, and the information provided lists multiple domains (basic, translational, clinical, prevention, population, behavioral, and others) as examples of the breadth.
Is this opportunity tied to standard NIH policies and timelines?
Yes. The information provided indicates applicants needed to plan around a traditional NIH application timeline and policies in effect for that period (with the record dates showing creation on September 3, 2015 and an original closing date of January 7, 2016).
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| NIDA Animal Genomics Program (U01 Clinical Trial Not Allowed) Apply for PAR 24 269 Funding Number: PAR 24 269 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Data Mining and Functional Validation (R21 Clinical Trial Not Allowed) Apply for RFA DA 26 002 Funding Number: RFA DA 26 002 Agency: National Institutes of Health Category: Education, Health Funding Amount: $275,000 |
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