Environmental Health Disparities Centers (P50) Clinical Trial Optional | RFA MD 24 010

Opportunity Information: Apply for RFA MD 24 010

The Environmental Health Disparities Centers (P50) Clinical Trial Optional funding opportunity (RFA-MD-24-010) is a National Institutes of Health (NIH) center grant designed to build and support multidisciplinary, community-engaged research programs focused on environmental health disparities and environmental justice. The core aim is to support coordinated research, research capacity building, and partnership-driven activities that address how environmental exposures and related social and structural factors contribute to unequal health outcomes in populations and communities experiencing health disparities across the United States and its territories. As a P50 center mechanism, the opportunity is oriented toward integrated, multi-project efforts rather than a single stand-alone study, encouraging teams that can connect scientific research with real-world community priorities and solutions.

The scope emphasizes three linked pillars: (1) multidisciplinary research on environmental health disparities and environmental justice, (2) research capacity building to strengthen the ability of institutions and communities to conduct and sustain this work, and (3) community-engaged research activities that involve affected communities in meaningful ways. The “clinical trial optional” designation signals that applicants may propose studies that include clinical trials if appropriate, but they are not required to do so. Overall, the opportunity is positioned for applicants who can bring together environmental health science, public health, clinical and translational perspectives when relevant, and community-based approaches to produce evidence and action that reduce inequities tied to environmental conditions.

Eligibility is broad and includes many types of domestic U.S. organizations and governmental entities. Eligible applicants listed include state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; Native American tribal organizations other than federally recognized tribal governments; nonprofits with and without 501(c)(3) status (excluding institutions of higher education in that specific nonprofit category); for-profit organizations other than small businesses; small businesses; and other organizations. The announcement also explicitly highlights additional eligible applicant categories, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), faith-based or community-based organizations, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), regional organizations, eligible federal government agencies, Indian/Native American Tribal Governments that are not federally recognized, and U.S. territories or possessions.

At the same time, the geographic and organizational limits are clear: non-domestic (non-U.S.) entities (foreign organizations) are not eligible to apply, non-domestic components of U.S. organizations are not eligible to apply, and foreign components as defined by the NIH Grants Policy Statement are not allowed. In practical terms, the work must be led by eligible U.S.-based applicants and carried out without foreign components under NIH definitions, reinforcing the program’s focus on disparities affecting communities within the U.S. and its territories.

Key administrative details provided include the opportunity category (discretionary), funding instrument type (grant), and broad funding activity areas (education, environment, health, income security, and social services). The associated CFDA numbers are 93.113, 93.307, 93.361, 93.393, 93.865, and 93.866. The original closing date listed is January 29, 2025, and the posting/creation date is October 21, 2024. No award ceiling or expected number of awards is specified in the provided source text, indicating applicants would need to consult the full announcement for budget limits, program structure expectations, and review criteria.

• The National Institutes of Health in the education, environment, health, income security and social services sector is offering a public funding opportunity titled "Environmental Health Disparities Centers (P50) Clinical Trial Optional" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.307, 93.361, 93.393, 93.865, 93.866.
• This funding opportunity was created on 2024-10-21.
• Applicants must submit their applications by 2025-01-29. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

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