Opportunity Information: Apply for PAR 18 771
The NHLBI Career Transition Award for Intramural Postdoctoral Fellows and Research Trainees (K22, Clinical Trial Required) is a National Institutes of Health grant opportunity designed specifically to help highly qualified postdoctoral fellows and research trainees working in the NHLBI Division of Intramural Research move from a mentored intramural training environment into an independent, faculty-style research position at an extramural institution. In practical terms, the program is meant to bridge the common gap between strong postdoctoral work at NIH and the launch of an independent research program elsewhere, giving investigators both time and structured support to build a publishable body of work, define a coherent research direction, and then establish that program at a university or other eligible US-based research organization. Because the FOA is labeled "Clinical Trial Required," applicants are expected to propose research that includes a clinical trial component consistent with NIH definitions and the specific requirements laid out in the full announcement.
The award is structured in two connected phases totaling up to five years of support. The first phase is a mentored intramural phase that can last up to two years while the investigator remains within NHLBI intramural research. This period is intended for intensive mentored development and productivity: completing key experiments, generating preliminary data, publishing, and shaping an independent research niche that can be carried forward. The second phase is an extramural phase that can last three years and takes place after the awardee secures an independent position at an eligible extramural institution. This extramural portion is intended to help the awardee establish their lab or research program, continue the proposed line of work, and build momentum toward longer-term independent funding.
A key feature of this K22 is that the move from the intramural phase to the extramural phase is not automatic. The transition requires NHLBI approval and is contingent on demonstrated progress during the mentored phase. NHLBI conducts a progress review that evaluates the success of the intramural research and also examines the proposed research plan for the extramural institution. That review functions as a go/no-go checkpoint, ensuring that the candidate has achieved sufficient scientific and professional development and that the planned extramural work is strong, feasible, and well-matched to the new independent setting. In other words, the award is designed to support a transition, but the applicant must earn that transition through performance and a convincing forward plan.
Eligibility is limited and notably excludes foreign participation. Non-domestic (non-US) entities (foreign institutions) are not eligible to apply, and non-domestic components of US organizations are also not eligible. In addition, foreign components as defined by the NIH Grants Policy Statement are not allowed under this opportunity. The eligible applicant type listed includes public and state-controlled institutions of higher education, reflecting the expectation that the extramural phase will be conducted at a qualifying US-based institution. The sponsoring agency is the National Institutes of Health, and the funding activity falls under health-related research categories, with CFDA numbers listed as 93.233 and 93.837 through 93.840. The opportunity number is PAR-18-771, created on 2018-05-09, with an original closing date shown as 2021-05-07. The public summary does not provide an award ceiling or expected number of awards, so those details would need to be confirmed in the full FOA text or related NHLBI guidance.
Overall, this K22 mechanism is best understood as a structured career launch program for NHLBI intramural trainees who are ready to move toward independence. It offers a defined runway: first, mentored support to solidify a competitive research package inside NHLBI, and second, time-limited extramural funding to help convert that package into a sustainable independent program. The built-in progress review and required approval for transition underscore that the award is performance-based, with continued support tied to clear research advancement and a credible plan for the independent phase.Apply for PAR 18 771
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NHLBI Career Transition Award for Intramural Postdoctoral Fellows and Research Trainees (K22 Clinical Trial Required)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.233, 93.837, 93.838, 93.839, 93.840.
- This funding opportunity was created on 2018-05-09.
- Applicants must submit their applications by 2021-05-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Public and State controlled institutions of higher education.
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| Funding Opportunity |
|---|
| Novel Genomic Technology Development (R43/R44 Clinical Trial Not Allowed) Apply for PAR 18 779 Funding Number: PAR 18 779 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Prevention Technology Transfer Centers Cooperative Agreements (Short Title: PTTC) Apply for SP 19 001 Funding Number: SP 19 001 Agency: Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $7,500,000 |
| NINDS Research Education Opportunities (R25 Clinical Trial Not Allowed) Apply for PAR 18 782 Funding Number: PAR 18 782 Agency: National Institutes of Health Category: Health Funding Amount: $250,000 |
| Collaborative Cross (CC) Mouse Model Generation and Discovery of Immunoregulatory Mechanisms (R21 Clinical Trials Not Allowed) Apply for PAR 18 781 Funding Number: PAR 18 781 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| Collaborative Network to Advance Deprescribing Research for Older Adults with Multiple Chronic Conditions (R24 Clinical Trial Optional) Apply for RFA AG 19 005 Funding Number: RFA AG 19 005 Agency: National Institutes of Health Category: Health Funding Amount: $1,000,000 |
| Mentored Research Scientist Career Development Award in Tobacco Regulatory Research (K01 - Independent Clinical Trial Not Allowed) Apply for RFA OD 18 005 Funding Number: RFA OD 18 005 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Mentored Research Scientist Career Development Award in Tobacco Regulatory Research (K01 - Independent Clinical Trial Required) Apply for RFA OD 18 006 Funding Number: RFA OD 18 006 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Wearable Alcohol Biosensors (SBIR) (R43/R44- Clinical Trial Optional) Apply for PA 18 786 Funding Number: PA 18 786 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Wearable Alcohol Biosensors (STTR) (R41/R42- Clinical Trial Optional) Apply for PA 18 785 Funding Number: PA 18 785 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Pathway to Independence Award in Tobacco Regulatory Research (K99/R00 - Independent Clinical Trial Required) Apply for RFA OD 18 008 Funding Number: RFA OD 18 008 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| The Mechanistic Role of the Microbiome in the Pathobiology of Heart, Lung, Blood, and Sleep Diseases (R01 - Clinical Trial Not Allowed) Apply for PA 18 784 Funding Number: PA 18 784 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Pathway to Independence Award in Tobacco Regulatory Research (K99/R00 - Independent Clinical Trial Not Allowed) Apply for RFA OD 18 007 Funding Number: RFA OD 18 007 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Precision Imaging of Oral Lesions (R21-Clinical Trial Not Allowed) Apply for PAR 18 788 Funding Number: PAR 18 788 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| USAID/Nigeria Orphans and Vulnerable Children Social Service Activities (OSSA) Apply for RFI 620 18 OVC Funding Number: RFI 620 18 OVC Agency: Nigeria USAID-Abuja Category: Health Funding Amount: $70,000,000 |
| Advancing Evidence into Practice through Shared, Interoperable Clinical Decision Support Resources (U18) Apply for PA 18 792 Funding Number: PA 18 792 Agency: Agency for Health Care Research and Quality Category: Health Funding Amount: $500,000 |
| AHRQ Small Research Grant Program (R03) Apply for PA 18 794 Funding Number: PA 18 794 Agency: Agency for Health Care Research and Quality Category: Health Funding Amount: $100,000 |
| AHRQ Health Services Research Projects (R01) Apply for PA 18 795 Funding Number: PA 18 795 Agency: Agency for Health Care Research and Quality Category: Health Funding Amount: $400,000 |
| AHRQ Health Services Research Demonstration and Dissemination Grants (R18) Apply for PA 18 793 Funding Number: PA 18 793 Agency: Agency for Health Care Research and Quality Category: Health Funding Amount: $400,000 |
| Biomarkers Discovery In Parkinsonism (U01 Clinical Trial Optional) Apply for PAR 18 800 Funding Number: PAR 18 800 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NIOSH Small Research Grant Program Apply for PAR 18 797 Funding Number: PAR 18 797 Agency: Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $50,000 |
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